Amitriptyline: still efficacious, but at what cost?
نویسنده
چکیده
منابع مشابه
Tricyclic Antidepressant-Induced Anticholinergic Delirium in a Young Healthy Male Individual
The tricyclic antidepressants, while older, still have their place in the treatment of depression today. They are efficacious but less selective and thus have the potential of eliciting many side effects. Anticholinergic delirium is a potential complication when using a tricyclic antidepressant or other anticholinergic agent. Following the Naranjo algorithm, this case report describes a probabl...
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BACKGROUND Amitriptyline has been replaced in many countries by alternative and more expensive drugs based on claims of improved tolerability and toxicity and despite slightly reduced efficacy. Preliminary studies indicate that adverse effects could be linked to polymorphisms of drug-metabolizing enzymes, but information on their clinical impact remains scanty and includes mainly case reports. ...
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ورودعنوان ژورنال:
- The British journal of psychiatry : the journal of mental science
دوره 178 شماره
صفحات -
تاریخ انتشار 2001